Nexium (esomeprazole magnesium) is a PPI medication used to reduce stomach acid and treat a range of conditions. First approved by the U.S. Food and Drug Administration (FDA) in February 2001,1 Nexium is made by AstraZeneca and Pfizer, Inc., and it is available via prescription, as well as over the counter (OTC). Nexium is one of many proton pump inhibitors that have been linked to serious side effects.
If you or a loved one has been seriously harmed after taking Nexium or any PPI, you can turn to the dangerous drug lawyers at the Amaro Law Firm for answers about your options for financial recovery and justice.
Tenacious and strategic, our attorneys have the insight and experience to provide you with effective advocacy while positioning your claim for any possible recovery.
Nexium and PPIs are acid reflux medications that have been linked to stroke and other serious complications. Patients harmed by these drugs may have a claim against Pfizer and others.
Nexium and other proton pump inhibitors work by turning “off” the pumps in the stomach that produce acid (for digestion). Unlike antacids that neutralize excessive stomach acid, Nexium and PPIs prevent the stomach from producing acid.
Consequently, Nexium and other PPIs are used to treat various conditions, like:
Acid reflux disease, gastroesophageal reflex disease (GERD) & heartburn, all of which are caused by stomach acid entering the esophagus
Erosive esophagitis, the erosion of the esophagus due to prolonged exposure to stomach acid
Stomach infection caused by the Helicobacter pylori (HP) bacteria
Stomach ulcers, which can be caused by an HP bacterial infection and/or prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs)
Zollinger-Ellison syndrome, a condition in which tumors in the pancreas or small intestines cause the stomach to produce excessive acid.
In addition to Nexium, brand names for other proton pump inhibitors include (and are not limited to):
AcipHex (rabeprazole), made by Eisai, Inc.
Dexilant (dexlansoprazole), made by Takeda Pharmaceuticals U.S.A., Inc. (Takeda)
Prevacid (lansoprazole), made by Takeda
Priolsec (omeprazole), made by Proctor & Gamble (P&G)
Protonix (pantoprazole), made by Pfizer
Zegerid (omeprazole/sodium bicarbonate), made by Bayer Pharmaceuticals.
Nexium and other PPIs can cause mild side effects, like (but not exclusive to):
Serious Nexium Side Effects & Complications
Nexium and other PPIs have been associated with some serious side effects, including (but not necessarily limited to):
Acute interstitial nephritis (AIN), serious inflammation of the kidneys – Marked by blood in the urine and bloating, AIN can lead to kidney failure.
Clostridium difficile-associated diarrhea (CDAD), a severe form of diarrhea caused by an intestinal infection known as clostridium difficile – CDAD can cause severe dehydration, kidney problems, colon blockage and bowel perforation. Without treatment, the most serious CDAD cases can be deadly.
Hypomagnesemia, dangerously low magnesium levels – This condition can impact nearly every biological system and potentially cause life-threatening complications, like arrhythmia and sudden death.
Cyanocobalamin, severe Vitamin B12 deficiencies – These deficiencies can result in memory loss, mood changes, depression and nervous system complications. In the most serious cases, Vitamin B12 deficiencies can lead to dementia.
Wrist, hip and spine fractures – The reduction of stomach acid caused by PPIs can result in reduced calcium absorption, increasing the risk of bone fractures.
System lupus erythematosus (SLE) events – These events can trigger the autoimmune system to attack the body’s tissues, causing inflammation on the face or extremities (particularly following sun exposure). If left untreated, this condition can cause organ failure.
Stroke – A 2016 study found that patients who were taking the highest available doses of Nexium and other PPIs had a 50 percent elevated risk of stroke.2
FDA Warnings about Nexium & Proton Pump Inhibitors
The FDA has taken various actions to warn the public about the many serious risks associated with taking Nexium and other PPIs. These include (but are not limited to):
An October 2016 Warning regarding the risks of SLE events3
Two December 2014 Safety Communications, with one pertaining the risks of AIN and the other related to the risks associated with cyanocobalamin4
A February 2012 Warning, alerting the public about the risks of CDAD5
A March 2011 Safety Communication regarding the risks of hypomagnesemia5
A May 2010 Alert, warning about the risks of spine, hip and bone fractures.5
Nexium Lawsuits & Multidistrict Litigation (MDL)
Hundreds of people have already taken action to file claims against AstraZeneca, Pfizer and other makers of PPI drugs, alleging that:
These medications caused them to develop severe health complications.
The drug makers were negligent in warning the public about the serious risks associated with Nexium and other PPIs.
As PPI claims have amassed in courts across the U.S., in August 2017, the Judicial Panel on Multidistrict Litigation (JPML) issued an order to transfer these actions to the U.S. District Court, District of New Jersey.6 The Proton Pump Inhibitor MDL (MDL No. 2789)7 is focused on facilitating discovery and pretrial proceedings for the many PPI claims that are currently pending.
Those who have a new Nexium or proton pump inhibitor claim may have the option to join the ongoing MDL or keep their case separate, depending on the details of their claim and other factors. An attorney at the Amaro Law Firm is ready to review your potential claim and explain your best options.
Find Out More about Your Rights & Legal Options: Contact a Dangerous Drug Lawyer at the Amaro Law Firm
A dangerous drug lawyer at the Amaro Law Firm is ready to help you successfully navigate the path to recovery and justice if you or a loved one has been seriously harmed by Nexium or any PPI drug.
Call (877) 892-2797, text (281) 612-8024 or email our firm for your FREE consultation and important answers regarding your potential claim.
With more than two decades of legal experience, our attorneys can provide you with exceptional advocacy as we help you obtain the financial recovery you deserve. While we are aware that no sum of money can ever reverse the permanent losses caused by PPIs, we also know that these recoveries can be the key to gaining justice and restoring lives.
The Amaro Law Firm’s record of effective representation and success in dangerous drug claims is affirmed by glowing testimonials from our former clients and our 5-star ratings on Google and Facebook.